OmniPath Get Ligand Receptor Interactions
Get ligand-receptor interaction pairs from OmniPath, the largest integrated intercellular communication database. Combines data from CellPhoneDB, CellChatDB, CellTalkDB, connectomeDB, Ramilowski2015, Guide2Pharma, HPMR, and 20+ other curated resources. Returns source/target proteins with directionality, stimulation/inhibition flags, supporting databases, and curation effort scores. Essential for cell-cell communication analysis in single-cell transcriptomics (CellPhoneDB/CellChat/LIANA workflow…
Overview
Get ligand-receptor interaction pairs from OmniPath, the largest integrated intercellular communication database. Combines data from CellPhoneDB, CellChatDB, CellTalkDB, connectomeDB, Ramilowski2015, Guide2Pharma, HPMR, and 20+ other curated resources. Returns source/target proteins with directionality, stimulation/inhibition flags, supporting databases, and curation effort scores. Essential for cell-cell communication analysis in single-cell transcriptomics (CellPhoneDB/CellChat/LIANA workflows). Example: querying TGFB1 returns 30 ligand-receptor interactions including TGFB1->TGFBR2 (135 curation effort, 34 databases), TGFB1->ACVRL1 (14 curation effort, 26 databases); querying CD274 (PD-L1) finds CD274->PDCD1 immune checkpoint interaction supported by 22 databases.
Schema
JSON Schema the agent (or your API call) must match.
Examples (1)
Default OmniPath Get Ligand Receptor Interactions call
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_OmniPath_get_ligand_receptor_interactions
- Tool name
- OmniPath_get_ligand_receptor_interactions
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse