OmniPath Get Ligand Receptor Interactions
Get ligand-receptor interaction pairs from OmniPath, the largest integrated intercellular communication database. Combines data from CellPhoneDB, CellChatDB, CellTalkDB, connectomeDB, Ramilowski2015, Guide2Pharma, HPMR, and 20+ other curated resources. Returns source/target proteins with directionality, stimulation/inhibition flags, supporting databases, and curation effort scores. Essential for cell-cell communication analysis in single-cell transcriptomics (CellPhoneDB/CellChat/LIANA workflow…
Overview
Get ligand-receptor interaction pairs from OmniPath, the largest integrated intercellular communication database. Combines data from CellPhoneDB, CellChatDB, CellTalkDB, connectomeDB, Ramilowski2015, Guide2Pharma, HPMR, and 20+ other curated resources. Returns source/target proteins with directionality, stimulation/inhibition flags, supporting databases, and curation effort scores. Essential for cell-cell communication analysis in single-cell transcriptomics (CellPhoneDB/CellChat/LIANA workflows). Example: querying TGFB1 returns 30 ligand-receptor interactions including TGFB1->TGFBR2 (135 curation effort, 34 databases), TGFB1->ACVRL1 (14 curation effort, 26 databases); querying CD274 (PD-L1) finds CD274->PDCD1 immune checkpoint interaction supported by 22 databases.
Schema
JSON Schema the agent (or your API call) must match.
View JSON schemaExpandCollapse
Examples (1)
Default OmniPath Get Ligand Receptor Interactions call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_OmniPath_get_ligand_receptor_interactions
- Tool name
- OmniPath_get_ligand_receptor_interactions
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse