Cortexa research tool·clinical·oncokb

OncoKB Annotate Copy Number

Annotate copy number alterations (amplification/deletion) for oncogenic potential. Returns evidence for gene amplification or deletion in cancer. Example: ERBB2 amplification in breast cancer, CDKN2A deletion.

Livelast probed 2026-05-01 01:00Z· 83msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 83ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "copy_number_alteration": {
      "description": "Alias for copy_number_type. Amplification or Deletion.",
      "type": "string"
    },
    "copy_number_type": {
      "description": "Type of copy number alteration (case-insensitive: AMPLIFICATION or DELETION)",
      "enum": [
        "AMPLIFICATION",
        "DELETION",
        "Amplification",
        "Deletion",
        "amplification",
        "deletion"
      ],
      "type": "string"
    },
    "gene": {
      "description": "Gene symbol (e.g., ERBB2, MYC, CDKN2A)",
      "type": "string"
    },
    "operation": {
      "const": "annotate_copy_number",
      "description": "Operation type (fixed: annotate_copy_number)",
      "type": "string"
    },
    "tumor_type": {
      "description": "Optional OncoTree tumor type code",
      "type": "string"
    }
  },
  "required": [
    "gene"
  ],
  "type": "object"
}

Examples (1)

Default OncoKB Annotate Copy Number call

public-safeinput

{
  "gene": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_OncoKB_annotate_copy_number
Tool name: OncoKB_annotate_copy_number
Added: 2026-05-01 00:58Z
Tags: tooluniverse

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "copy_number_alteration": { "description": "Alias for copy_number_type. Amplification or Deletion.", "type": "string" }, "copy_number_type": { "description": "Type of copy number alteration (case-insensitive: AMPLIFICATION or DELETION)", "enum": [ "AMPLIFICATION", "DELETION", "Amplification", "Deletion", "amplification", "deletion" ], "type": "string" }, "gene": { "description": "Gene symbol (e.g., ERBB2, MYC, CDKN2A)", "type": "string" }, "operation": { "const": "annotate_copy_number", "description": "Operation type (fixed: annotate_copy_number)", "type": "string" }, "tumor_type": { "description": "Optional OncoTree tumor type code", "type": "string" } }, "required": [ "gene" ], "type": "object" }