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Cortexa research tool·genomics·opencravat
OpenCRAVAT Annotate Variant
Annotate a single genomic variant using OpenCRAVAT with 182+ annotation sources including ClinVar, gnomAD, SIFT, PolyPhen-2, REVEL, AlphaMissense, SpliceAI, GERP, PhastCons, DANN, FATHMM, and more. Returns gene name, amino acid change, consequence type, and all requested annotator results. Input: chromosome, position (1-based, GRCh38), reference and alternate alleles. Optionally specify which annotators to use (comma-separated).
AvailableCortexa
Schema
JSON Schema the agent (or your API call) must match.
JSON · 69 lines · 1,775 chars
Examples (1)
Default OpenCRAVAT Annotate Variant call
public-safeinput
JSON · 1 line · 2 chars
Expected response keys: success
Anonymous-safe example. Rate-limited; no sign-in required.
Identifiers
- Catalog ID
- tu_OpenCRAVAT_annotate_variant
- Tool name
- OpenCRAVAT_annotate_variant
- Added
- 2026-04-30 22:47Z
- Tags
- tooluniverse