OpenTargets Get Evidence By Datasource

Overview

Get target-disease evidence from Open Targets filtered by configurable data sources. Unlike OpenTargets_target_disease_evidence (intogen-only), this tool accepts any datasourceIds. Valid sources include: ot_genetics_portal, eva, eva_somatic, gene_burden, genomics_england, intogen, cancer_gene_census, chembl, crispr, europepmc, expression_atlas, gene2phenotype, orphanet, uniprot_literature, uniprot_variants, clingen, phewas_catalog, reactome, progeny, slapenrich, sysbio. Returns evidence rows with scores, literature references, and source attribution.

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

577ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "datasourceIds": {
      "description": "List of datasource IDs to filter evidence. Examples: ['chembl', 'europepmc'], ['eva', 'clinvar'], ['intogen', 'cancer_gene_census']. Omit or pass empty array for all sources.",
      "items": {
        "type": "string"
      },
      "type": "array"
    },
    "disease_name": {
      "description": "Disease or phenotype name (e.g., 'Crohn disease'). Auto-resolved to efoId.",
      "type": "string"
    },
    "efoId": {
      "description": "Disease EFO ID (e.g., 'EFO_0000384' for Crohn's disease). Alternative to disease_name.",
      "type": "string"
    },
    "ensemblId": {
      "description": "Target Ensembl gene ID (e.g., 'ENSG00000141510' for TP53). Alternative to gene_symbol.",
      "type": "string"
    },
    "gene_symbol": {
      "description": "HGNC gene symbol (e.g., 'TP53', 'BRCA1'). Auto-resolved to ensemblId.",
      "type": "string"
    },
    "size": {
      "default": 50,
      "description": "Maximum evidence rows to return (default: 50)",
      "type": "integer"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

{
  "datasourceIds": [],
  "disease_name": "type 2 diabetes",
  "gene_symbol": "BRCA1",
  "size": 1
}

Identifiers

Catalog ID

tu_OpenTargets_get_evidence_by_datasource

Tool name

OpenTargets_get_evidence_by_datasource

Added

2026-04-30 22:47Z

Tags

tooluniverse