Cortexa research tool·drug discovery·opentarget_genetics

OpenTargets Get Variant Credible Sets

Get GWAS credible sets (fine-mapped loci) associated with a genetic variant from Open Targets. Returns studies where this variant appears in a fine-mapped credible set, with locus-to-gene (L2G) predictions, p-values, effect sizes, and the fine-mapping method used. Essential for understanding which GWAS signals a variant is part of and which genes it likely affects.

Livelast probed 2026-04-30 23:07Z· 94msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 94ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "size": {
      "default": 10,
      "description": "Number of credible sets to return (default 10)",
      "type": "integer"
    },
    "variantId": {
      "description": "Open Targets variant ID in format chr_position_ref_alt (e.g., '10_112998590_C_T' for rs7903146)",
      "type": "string"
    }
  },
  "required": [
    "variantId"
  ],
  "type": "object"
}

Examples (1)

Default OpenTargets Get Variant Credible Sets call

public-safeinput

{
  "size": 1,
  "variantId": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_OpenTargets_get_variant_credible_sets
Tool name: OpenTargets_get_variant_credible_sets
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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