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Research tool·drug discovery·opentarget_genetics

OpenTargets Get Variant Effect Predictions

Retrieve in-silico functional effect predictions for a variant (chrom_pos_ref_alt) from OpenTargets. Returns one record per prediction method (VEP, SIFT, PolyPhen, AlphaMissense, FoldX, GERP, CADD, etc.), each with an assessment (e.g. 'missense_variant', 'deleterious', 'tolerated') and a numeric score. Use to judge whether a variant is likely damaging.

AvailableCortexa

Schema

JSON Schema the agent (or your API call) must match.

View JSON schemaExpandCollapse
JSON · 12 lines · 248 chars

Examples (1)

Default OpenTargets Get Variant Effect Predictions call

Public-safe example · rate-limited

JSON input · 3 lines · 36 chars
Expected response keys: success

Identifiers

Catalog ID
tu_OpenTargets_get_variant_effect_predictions
Tool name
OpenTargets_get_variant_effect_predictions
Added
2026-07-29 18:13Z
Tags
tooluniverse
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