Cortexa research tool·genomics·orthodb

OrthoDB Search Groups

Search for orthologous groups by gene/protein name in OrthoDB v12. OrthoDB catalogs orthologous groups at different taxonomic levels (vertebrates, metazoa, eukaryotes, etc.), enabling evolutionary analysis of gene conservation. Returns group IDs that can be queried for details. Complements OMA and Ensembl Compara with group-level orthology at deep evolutionary scales. Example: searching 'BRCA1' with species=9606 returns orthologous groups containing BRCA1 at various taxonomic levels.

Livelast probed 2026-05-01 01:00Z· 2412msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 2412ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "level": {
      "description": "Taxonomic level for group definition. Examples: 7742 (Vertebrata), 33208 (Metazoa), 2759 (Eukaryota). Null for all levels.",
      "type": [
        "integer",
        "null"
      ]
    },
    "limit": {
      "description": "Maximum number of groups to return (1-50). Default: 10.",
      "type": "integer"
    },
    "query": {
      "description": "Gene or protein name to search. Examples: 'BRCA1', 'TP53', 'insulin', 'EGFR'.",
      "type": "string"
    },
    "species": {
      "description": "NCBI taxonomy ID to filter by species. Examples: 9606 (human), 10090 (mouse), 7227 (fly). Null for all species.",
      "type": [
        "integer",
        "null"
      ]
    }
  },
  "required": [
    "query"
  ],
  "type": "object"
}

Examples (1)

Default OrthoDB Search Groups call

public-safeinput

{
  "limit": 3,
  "query": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_OrthoDB_search_groups
Tool name: OrthoDB_search_groups
Added: 2026-05-01 00:58Z
Tags: tooluniverse

OrthoDB Search Groups

Livelast probed 2026-05-01 01:00Z· 2412msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "level": { "description": "Taxonomic level for group definition. Examples: 7742 (Vertebrata), 33208 (Metazoa), 2759 (Eukaryota). Null for all levels.", "type": [ "integer", "null" ] }, "limit": { "description": "Maximum number of groups to return (1-50). Default: 10.", "type": "integer" }, "query": { "description": "Gene or protein name to search. Examples: 'BRCA1', 'TP53', 'insulin', 'EGFR'.", "type": "string" }, "species": { "description": "NCBI taxonomy ID to filter by species. Examples: 9606 (human), 10090 (mouse), 7227 (fly). Null for all species.", "type": [ "integer", "null" ] } }, "required": [ "query" ], "type": "object" }