PANTHER Enrichment

Perform gene set enrichment (overrepresentation) analysis using PANTHER. Given a gene list, identifies statistically enriched GO terms, PANTHER pathways, Reactome pathways, or protein classes using Fisher's exact test with FDR correction. PANTHER is one of the most widely used tools for functional enrichment in bioinformatics. Example: gene list 'TP53,BRCA1,EGFR,KRAS,PTEN' enriched for GO biological_process returns 'regulation of mitotic cell cycle phase transition' (FDR=0.003).