Cortexa research tool·structure·pdbe_kb

PDBe KB Get Interface Residues

Get protein-protein interaction interface residues for a UniProt protein from PDBe-KB. Returns residue positions (UniProt numbering) at interaction interfaces with other proteins, the identity of interaction partners, and PDB structures where each interface was observed. Essential for understanding protein complex formation, designing interface-disrupting mutations, and identifying functional hotspots. Example: P04637 (TP53) shows interaction interfaces with MDM2, p53BP2, and DNA.

Livelast probed 2026-04-30 23:07Z· 117msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 117ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "uniprot_accession": {
      "description": "UniProt accession ID for the protein. Examples: 'P04637' (TP53), 'P00533' (EGFR), 'P38398' (BRCA1).",
      "type": "string"
    }
  },
  "required": [
    "uniprot_accession"
  ],
  "type": "object"
}

Examples (1)

Default PDBe KB Get Interface Residues call

public-safeinput

{
  "uniprot_accession": "P38398"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_PDBe_KB_get_interface_residues
Tool name: PDBe_KB_get_interface_residues
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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