Cortexa research tool·drug discovery·pharmgkb

PharmGKB Get Dosing Guidelines

Get pharmacogenetic dosing guidelines (CPIC/DPWG) from PharmGKB by guideline_id. IMPORTANT: use the 'clinpgxid' field from CPIC_list_guidelines (e.g., 'PA166251454'), NOT the 'pharmgkbid' field — old-format pharmgkbid values (e.g., 'PA166104996') return HTTP 404. The test example PA166251465 is for the warfarin guideline.

Livelast probed 2026-04-30 23:07Z· 107msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 107ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "gene": {
      "description": "Gene symbol (e.g., 'CYP2D6'). NOTE: Filtering by gene symbol is unreliable and may return a generic prompt instead of actual guidelines. Use guideline_id instead.",
      "type": "string"
    },
    "guideline_id": {
      "description": "PharmGKB ClinPGx guideline ID from CPIC_list_guidelines 'clinpgxid' field (e.g., 'PA166251465' for warfarin, 'PA166251454' for opioids/codeine, 'PA166251458' for tamoxifen). Use clinpgxid, NOT pharmgkbid.",
      "type": "string"
    }
  },
  "required": [
    "guideline_id"
  ],
  "type": "object"
}

Examples (1)

Default PharmGKB Get Dosing Guidelines call

public-safeinput

{
  "gene": "BRCA1",
  "guideline_id": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_PharmGKB_get_dosing_guidelines
Tool name: PharmGKB_get_dosing_guidelines
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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