Cortexa research tool·genomics·protvar

ProtVar Get Population

Get population observation data for a protein variant position from ProtVar. Returns co-located variants with population allele frequencies (gnomAD, 1000Genomes), clinical significance (ClinVar), and computational predictions (SIFT, PolyPhen).

Livelast probed 2026-04-30 23:07Z· 92msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 92ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "accession": {
      "description": "UniProt accession (e.g. 'P22304' for IDS).",
      "type": "string"
    },
    "genomic_location": {
      "description": "Genomic coordinate (GRCh38) for the variant. Obtain from ProtVar_map_variant output.",
      "type": "integer"
    },
    "position": {
      "description": "Amino acid position in the protein (1-based).",
      "type": "integer"
    }
  },
  "required": [
    "accession",
    "position",
    "genomic_location"
  ],
  "type": "object"
}

Examples (1)

Default ProtVar Get Population call

public-safeinput

{
  "accession": "P38398",
  "genomic_location": 1,
  "position": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_ProtVar_get_population
Tool name: ProtVar_get_population
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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