Cortexa research tool·chemistry·reactome_interactors

ReactomeInteractors Get Protein Interactors

Get protein-protein interaction partners for a specific protein from Reactome's IntAct-derived interaction data. Returns interactor accessions, gene names, confidence scores, and evidence counts. Interactions are curated from experimental data with molecular interaction (MI) scores. Example: get interactors for P04637 (TP53) returns 248 interactors including MDM2 (score 0.995, 119 evidences), EP300 (score 0.976), BRCA1 (score 0.944); for Q04206 (NF-kB p65/RELA) returns 105 interactors.

Livelast probed 2026-04-30 23:07Z· 89msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 89ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "accession": {
      "description": "UniProt accession number for the query protein. Examples: 'P04637' (TP53), 'Q04206' (NF-kB p65), 'P00533' (EGFR), 'P38398' (BRCA1).",
      "type": "string"
    },
    "page_size": {
      "description": "Maximum number of interactors to return (default: 20, max: 100).",
      "type": [
        "integer",
        "null"
      ]
    }
  },
  "required": [
    "accession"
  ],
  "type": "object"
}

Examples (1)

Default ReactomeInteractors Get Protein Interactors call

public-safeinput

{
  "accession": "P38398"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_ReactomeInteractors_get_protein_interactors
Tool name: ReactomeInteractors_get_protein_interactors
Added: 2026-04-30 22:47Z
Tags: tooluniverse

ReactomeInteractors Get Protein Interactors

Livelast probed 2026-04-30 23:07Z· 89msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "accession": { "description": "UniProt accession number for the query protein. Examples: 'P04637' (TP53), 'Q04206' (NF-kB p65), 'P00533' (EGFR), 'P38398' (BRCA1).", "type": "string" }, "page_size": { "description": "Maximum number of interactors to return (default: 20, max: 100).", "type": [ "integer", "null" ] } }, "required": [ "accession" ], "type": "object" }