Cortexa research tool·chemistry·rhea

Rhea Search Reactions

Search for biochemical reactions in the Rhea database by compound name, reaction description, or keyword. Rhea is an expert-curated knowledgebase of over 15,000 chemical and transport reactions of biological interest maintained by SIB Swiss Institute of Bioinformatics. All reactions are linked to ChEBI compounds and EC enzyme numbers. Example: searching 'glucose' returns reactions like 'D-glucose + NAD(+) = D-glucono-1,5-lactone + NADH + H(+)' with EC:1.1.1.47.

Livelast probed 2026-05-01 01:00Z· 78msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 78ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "limit": {
      "description": "Maximum number of results (default 20, max 50).",
      "type": [
        "integer",
        "null"
      ]
    },
    "query": {
      "description": "Search keyword for reactions. Can be a compound name, reaction term, or general keyword. Examples: 'glucose', 'ATP', 'kinase', 'ethanol', 'acetyl-CoA', 'phosphorylation'.",
      "type": "string"
    }
  },
  "required": [
    "query"
  ],
  "type": "object"
}

Examples (1)

Default Rhea Search Reactions call

public-safeinput

{
  "query": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_Rhea_search_reactions
Tool name: Rhea_search_reactions
Added: 2026-05-01 00:58Z
Tags: tooluniverse

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