STRING Get Functional Annotations

Overview

Get comprehensive functional annotations for a protein from STRING database. Returns per-protein annotations from Gene Ontology (Process, Function, Component), KEGG pathways, Reactome, WikiPathways, InterPro domains, Pfam, HPO phenotypes, DISEASES, TISSUES expression, and COMPARTMENTS subcellular localization. Different from STRING_functional_enrichment which tests for statistical enrichment of a protein SET - this tool returns all known annotations for individual proteins. Example: 'TP53' returns 1,877 annotations across 13 categories including 655 biological processes, 462 HPO phenotypes, 212 disease associations.

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed

1d ago

Last success

1d ago

Last latency

108ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "category": {
      "description": "Filter by annotation category. Options: 'Process' (GO BP), 'Function' (GO MF), 'Component' (GO CC), 'KEGG', 'RCTM' (Reactome), 'WikiPathways', 'InterPro', 'Pfam', 'HPO', 'DISEASES', 'TISSUES', 'COMPARTMENTS', 'Keyword'. Leave null for all categories.",
      "type": "string"
    },
    "identifiers": {
      "description": "Protein identifier (gene name or STRING ID). Examples: 'TP53', 'BRCA1', 'EGFR', '9606.ENSP00000269305'.",
      "type": "string"
    },
    "species": {
      "default": 9606,
      "description": "NCBI taxonomy ID (default 9606 for human). Examples: 9606 (human), 10090 (mouse), 7227 (fly), 6239 (worm).",
      "type": "integer"
    }
  },
  "required": [
    "identifiers"
  ],
  "type": "object"
}

Examples (1)

{
  "identifiers": "",
  "species": 1
}

Identifiers

Catalog ID

tu_STRING_get_functional_annotations

Tool name

STRING_get_functional_annotations

Added

2026-04-30 22:47Z

Tags

tooluniverse