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Research tool·genomics·synergxdb

SYNERGxDB Get Biomarker Association

Pharmacogenomic biomarker discovery for drug combinations in SYNERGxDB: correlates per-cell-line gene expression (rnaseq FPKM) against the measured drug-combination synergy scores (Bliss, Loewe, HSA, ZIP) for a queried gene. Answers 'does expression of gene X track with combination synergy across cancer cell lines?'. Returns one row per cell line with that cell line's FPKM for the gene plus its synergy metrics. Pass the HGNC gene symbol via 'gene' (e.g., 'EGFR', 'BRAF'). Example: gene='EGFR' re…

AvailableCortexa

Overview

Pharmacogenomic biomarker discovery for drug combinations in SYNERGxDB: correlates per-cell-line gene expression (rnaseq FPKM) against the measured drug-combination synergy scores (Bliss, Loewe, HSA, ZIP) for a queried gene. Answers 'does expression of gene X track with combination synergy across cancer cell lines?'. Returns one row per cell line with that cell line's FPKM for the gene plus its synergy metrics. Pass the HGNC gene symbol via 'gene' (e.g., 'EGFR', 'BRAF'). Example: gene='EGFR' returns rows like {fpkm:0, cellName:'A2058', bliss:-1.365, loewe:-0.259, hsa:-0.628, zip:-0.498}. An unknown gene returns an empty list with a message.

Schema

JSON Schema the agent (or your API call) must match.

View JSON schemaExpandCollapse
JSON · 23 lines · 508 chars

Examples (1)

Default SYNERGxDB Get Biomarker Association call

Public-safe example · rate-limited

JSON input · 5 lines · 88 chars
Expected response keys: success

Identifiers

Catalog ID
tu_SYNERGxDB_get_biomarker_association
Tool name
SYNERGxDB_get_biomarker_association
Added
2026-07-29 18:13Z
Tags
tooluniverse
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