SYNERGxDB Search Combos
Search drug combination synergy scores in SYNERGxDB. Returns synergy metrics (Bliss, Loewe, HSA, ZIP) for drug pairs across cancer cell lines. Filter by drug IDs, cell line/tissue, and dataset. The database integrates 22,507 unique drug combinations from 9 major studies (NCI-ALMANAC, MERCK, MIT-MELANOMA, VISAGE, DECREASE, YALE-TNBC, YALE-PDAC, STANFORD, CLOUD). Positive ZIP scores indicate synergy. Use list_drugs first to find drug IDs. NOTE: SYNERGxDB covers pairwise in vitro cytotoxicity scre…
Overview
Search drug combination synergy scores in SYNERGxDB. Returns synergy metrics (Bliss, Loewe, HSA, ZIP) for drug pairs across cancer cell lines. Filter by drug IDs, cell line/tissue, and dataset. The database integrates 22,507 unique drug combinations from 9 major studies (NCI-ALMANAC, MERCK, MIT-MELANOMA, VISAGE, DECREASE, YALE-TNBC, YALE-PDAC, STANFORD, CLOUD). Positive ZIP scores indicate synergy. Use list_drugs first to find drug IDs. NOTE: SYNERGxDB covers pairwise in vitro cytotoxicity screening; standard-of-care clinical regimens (FOLFOX, FOLFIRI, CAPOX, R-CHOP) and most targeted therapies/biologics (BRAF/MEK/KRAS inhibitors, immune checkpoint inhibitors, monoclonal antibodies) are not represented.
Schema
JSON Schema the agent (or your API call) must match.
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Examples (1)
Default SYNERGxDB Search Combos call
Public-safe example · rate-limited
Identifiers
- Catalog ID
- tu_SYNERGxDB_search_combos
- Tool name
- SYNERGxDB_search_combos
- Added
- 2026-05-01 00:58Z
- Tags
- tooluniverse