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Cortexa research tool·drug discovery·swissadme

SwissADME Calculate Adme

Compute ADMET properties, drug-likeness, and medicinal chemistry friendliness of a small molecule from its SMILES string using SwissADME. Returns 49 properties across 6 categories: physicochemical properties (MW, TPSA, rotatable bonds, H-bond donors/acceptors), lipophilicity (iLOGP, XLOGP3, WLOGP, MLOGP, consensus LogP), water solubility (ESOL, Ali, Silicos-IT with log S, mg/ml, mol/l, and class), pharmacokinetics (GI absorption, BBB permeation, Pgp substrate, CYP1A2/2C19/2C9/2D6/3A4 inhibition…

AvailableCortexa

Overview

Compute ADMET properties, drug-likeness, and medicinal chemistry friendliness of a small molecule from its SMILES string using SwissADME. Returns 49 properties across 6 categories: physicochemical properties (MW, TPSA, rotatable bonds, H-bond donors/acceptors), lipophilicity (iLOGP, XLOGP3, WLOGP, MLOGP, consensus LogP), water solubility (ESOL, Ali, Silicos-IT with log S, mg/ml, mol/l, and class), pharmacokinetics (GI absorption, BBB permeation, Pgp substrate, CYP1A2/2C19/2C9/2D6/3A4 inhibition, skin permeation), drug-likeness (Lipinski, Ghose, Veber, Egan, Muegge rule violations, bioavailability score), and medicinal chemistry (PAINS alerts, Brenk alerts, leadlikeness, synthetic accessibility). Computation takes 5-15 seconds.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 27 lines · 705 chars

Examples (1)

Default SwissADME Calculate Adme call

public-safeinput
JSON · 4 lines · 58 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_SwissADME_calculate_adme
Tool name
SwissADME_calculate_adme
Added
2026-04-30 22:47Z
Tags
tooluniverse
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