Cortexa research tool·clinical·timer

TIMER2 Gene Correlation

Analyze Spearman correlation between two genes across TCGA cancer samples using cBioPortal data. Returns correlation coefficient and p-value. Useful for identifying co-expressed genes in tumor microenvironment. Note: TIMER2.0/3.0 REST API is no longer public; uses cBioPortal as data source. Example: Correlate CD8A and PDCD1 expression in BRCA.

Livelast probed 2026-04-30 23:07Z· 96msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 96ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "cancer": {
      "description": "TCGA cancer type (e.g., 'BRCA', 'LUAD')",
      "type": "string"
    },
    "gene1": {
      "description": "First gene symbol (e.g., 'CD8A')",
      "type": "string"
    },
    "gene2": {
      "description": "Second gene symbol (e.g., 'PDCD1')",
      "type": "string"
    },
    "operation": {
      "description": "Operation type",
      "enum": [
        "gene_correlation"
      ],
      "type": "string"
    }
  },
  "required": [
    "operation",
    "cancer",
    "gene1",
    "gene2"
  ],
  "type": "object"
}

Examples (1)

Default TIMER2 Gene Correlation call

public-safeinput

{
  "cancer": "",
  "gene1": "BRCA1",
  "gene2": "BRCA1",
  "operation": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_TIMER2_gene_correlation
Tool name: TIMER2_gene_correlation
Added: 2026-04-30 22:47Z
Tags: tooluniverse

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