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Research tool·structure·unichem

UniChem Connectivity Search

Connectivity (cross-source) search in UniChem: find all compounds across the 40+ source databases that share the same connectivity layer as the query - i.e. salts, stereoisomers, tautomers, and charge/protonation/isotope variants of the input structure. Each returned match carries a per-match 'comparison' object of boolean flags (charge, connectivity, formula, isotope, protonation, stereoDbond, stereoSp3, HAtoms, ...) showing exactly how that match differs from the query. Use this (rather than…

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Overview

Connectivity (cross-source) search in UniChem: find all compounds across the 40+ source databases that share the same connectivity layer as the query - i.e. salts, stereoisomers, tautomers, and charge/protonation/isotope variants of the input structure. Each returned match carries a per-match 'comparison' object of boolean flags (charge, connectivity, formula, isotope, protonation, stereoDbond, stereoSp3, HAtoms, ...) showing exactly how that match differs from the query. Use this (rather than UniChem_search_compound, which does exact-structure matching) to discover related forms of a molecule across databases. Example: aspirin InChIKey 'BSYNRYMUTXBXSQ-UHFFFAOYSA-N' returns response 'Success' with totalCompounds 15 across 1044 source entries.

Schema

JSON Schema the agent (or your API call) must match.

JSON · 24 lines · 724 chars

Examples (1)

Default UniChem Connectivity Search call

public-safeinput
JSON · 5 lines · 86 chars
Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID
tu_UniChem_connectivity_search
Tool name
UniChem_connectivity_search
Added
2026-07-29 18:13Z
Tags
tooluniverse
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