ZINC Search By Properties

Filter ZINC compounds by molecular properties (Lipinski Rule of Five, Veber rules). Specify ranges for molecular weight, LogP, hydrogen bond donors/acceptors, and rotatable bonds. Optionally restrict to a purchasability tier. Useful for finding drug-like compounds: Lipinski (MW<500, LogP<5, HBD<5, HBA<10), fragment-like (MW<250, LogP<3), or lead-like (MW 250-350, LogP 1-3).