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Research tool·structure·zinc

ZINC Search By Smiles

Structure-search the ZINC22 (and legacy ZINC20) database by SMILES via the CartBlanche22 async structure-search API. Submits the query, polls for completion (within 30s), and returns matching compounds with zinc_id, SMILES, the matched substructure SMILES, formula, MW, LogP, InChIKey, source database, and vendor-catalog count. Use dist=0 (default) for exact matches and a small positive dist (e.g. 1-4) for graph-edit-distance similarity; adist is the anonymized (atom-type-agnostic) distance. Ret…

AvailableCortexa

Overview

Structure-search the ZINC22 (and legacy ZINC20) database by SMILES via the CartBlanche22 async structure-search API. Submits the query, polls for completion (within 30s), and returns matching compounds with zinc_id, SMILES, the matched substructure SMILES, formula, MW, LogP, InChIKey, source database, and vendor-catalog count. Use dist=0 (default) for exact matches and a small positive dist (e.g. 1-4) for graph-edit-distance similarity; adist is the anonymized (atom-type-agnostic) distance. Returns the ZINC IDs you then feed to ZINC_get_compound / ZINC_get_purchasable. Replaces the retired zinc15.docking.org service.

Schema

JSON Schema the agent (or your API call) must match.

View JSON schemaExpandCollapse
JSON · 46 lines · 1,243 chars

Examples (1)

Default ZINC Search By Smiles call

input
JSON · 8 lines · 147 chars
Expected response keys: success

Identifiers

Catalog ID
tu_ZINC_search_by_smiles
Tool name
ZINC_search_by_smiles
Added
2026-04-30 22:47Z
Tags
tooluniverse, slow
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