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Research tool·genomics·gprofiler

GProfiler Enrichment

Perform functional enrichment analysis on a gene list using g:Profiler (g:GOSt) from the University of Tartu. Identifies statistically overrepresented biological functions, pathways, and phenotypes in your gene list. Supports multiple data sources: Gene Ontology (GO:BP, GO:MF, GO:CC), KEGG pathways, Reactome, WikiPathways, Human Phenotype Ontology (HP), miRNA targets (MIRNA), CORUM protein complexes, and Transcription Factor targets (TF). Returns enriched terms with p-values (g:SCS multiple tes…

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Overview

Perform functional enrichment analysis on a gene list using g:Profiler (g:GOSt) from the University of Tartu. Identifies statistically overrepresented biological functions, pathways, and phenotypes in your gene list. Supports multiple data sources: Gene Ontology (GO:BP, GO:MF, GO:CC), KEGG pathways, Reactome, WikiPathways, Human Phenotype Ontology (HP), miRNA targets (MIRNA), CORUM protein complexes, and Transcription Factor targets (TF). Returns enriched terms with p-values (g:SCS multiple testing correction), term sizes, intersection genes, precision, and recall. Input is a comma-separated string of gene symbols (e.g., 'TP53,BRCA1,EGFR,KRAS,PTEN') -- a JSON array is not accepted. Supports 500+ organisms (use NCBI taxonomy prefix, e.g., 'hsapiens', 'mmusculus', 'dmelanogaster').

Schema

JSON Schema the agent (or your API call) must match.

View JSON schemaExpandCollapse
JSON · 20 lines · 723 chars

Examples (1)

Default GProfiler Enrichment call

Public-safe example · rate-limited

JSON input · 4 lines · 52 chars
Expected response keys: success

Identifiers

Catalog ID
tu_gProfiler_enrichment
Tool name
gProfiler_enrichment
Added
2026-04-30 22:47Z
Tags
tooluniverse
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