Cortexa research tool·genomics·gprofiler

GProfiler Find Orthologs

Find orthologous genes across species using g:Profiler (g:Orth) from the University of Tartu. Maps genes from a source organism to their orthologs in a target organism using Ensembl orthology data. Useful for translating gene lists between model organisms. Example: find mouse orthologs of human TP53 and BRCA1. Supports 500+ organisms in the Ensembl database. Input is a list of gene identifiers from the source organism, and the target organism to map to.

Livelast probed 2026-05-01 01:00Z· 1155msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 1155ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "gene_list": {
      "description": "Comma-separated list of gene identifiers from the source organism. Examples: 'TP53,BRCA1,EGFR' (human genes to find mouse orthologs).",
      "type": "string"
    },
    "source_organism": {
      "description": "Source organism. Default: 'hsapiens'. Examples: 'hsapiens' (human), 'mmusculus' (mouse).",
      "type": "string"
    },
    "target_organism": {
      "description": "Target organism to find orthologs in. Default: 'mmusculus'. Examples: 'mmusculus' (mouse), 'rnorvegicus' (rat), 'drerio' (zebrafish), 'dmelanogaster' (fly), 'celegans' (worm).",
      "type": "string"
    }
  },
  "required": [
    "gene_list"
  ],
  "type": "object"
}

Examples (1)

Default GProfiler Find Orthologs call

public-safeinput

{
  "gene_list": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_gProfiler_find_orthologs
Tool name: gProfiler_find_orthologs
Added: 2026-05-01 00:58Z
Tags: tooluniverse

GProfiler Find Orthologs

Livelast probed 2026-05-01 01:00Z· 1155msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "gene_list": { "description": "Comma-separated list of gene identifiers from the source organism. Examples: 'TP53,BRCA1,EGFR' (human genes to find mouse orthologs).", "type": "string" }, "source_organism": { "description": "Source organism. Default: 'hsapiens'. Examples: 'hsapiens' (human), 'mmusculus' (mouse).", "type": "string" }, "target_organism": { "description": "Target organism to find orthologs in. Default: 'mmusculus'. Examples: 'mmusculus' (mouse), 'rnorvegicus' (rat), 'drerio' (zebrafish), 'dmelanogaster' (fly), 'celegans' (worm).", "type": "string" } }, "required": [ "gene_list" ], "type": "object" }