Cortexa research tool·genomics·iptmnet

IPTMnet Get Ptm Ppi

Get PTM-dependent protein-protein interactions from iPTMnet. Returns interactions where a post-translational modification on one protein affects its binding to another protein. Each interaction includes the PTM type, modified substrate with site position, the interacting partner, association type (association/dissociation), data source, and PubMed reference. Essential for understanding how PTMs regulate protein interaction networks. Use with UniProt accession (e.g., P04637 for TP53).

Livelast probed 2026-04-30 23:07Z· 705msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 705ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "operation": {
      "description": "Operation type",
      "enum": [
        "get_ptm_ppi"
      ],
      "type": "string"
    },
    "ptm_type": {
      "description": "Filter by PTM type: Phosphorylation, Acetylation, Ubiquitination, Methylation. Case-insensitive. Omit to return all types.",
      "type": [
        "string",
        "null"
      ]
    },
    "uniprot_id": {
      "description": "UniProt accession, e.g., P04637 (TP53), P00533 (EGFR), P31749 (AKT1)",
      "type": "string"
    }
  },
  "required": [
    "operation",
    "uniprot_id"
  ],
  "type": "object"
}

Examples (1)

Default IPTMnet Get Ptm Ppi call

public-safeinput

{
  "operation": "",
  "uniprot_id": ""
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_iPTMnet_get_ptm_ppi
Tool name: iPTMnet_get_ptm_ppi
Added: 2026-04-30 22:47Z
Tags: tooluniverse

IPTMnet Get Ptm Ppi

Livelast probed 2026-04-30 23:07Z· 705msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "operation": { "description": "Operation type", "enum": [ "get_ptm_ppi" ], "type": "string" }, "ptm_type": { "description": "Filter by PTM type: Phosphorylation, Acetylation, Ubiquitination, Methylation. Case-insensitive. Omit to return all types.", "type": [ "string", "null" ] }, "uniprot_id": { "description": "UniProt accession, e.g., P04637 (TP53), P00533 (EGFR), P31749 (AKT1)", "type": "string" } }, "required": [ "operation", "uniprot_id" ], "type": "object" }