Cortexa research tool·genomics·iptmnet

IPTMnet Search

Search the iPTMnet database for proteins with post-translational modification (PTM) data. Find proteins by gene name, protein name, or keyword. Filter by role (Substrate = modified protein, Enzyme = modifier) and PTM type (Phosphorylation, Acetylation, Ubiquitination, Methylation, etc.). iPTMnet integrates data from PhosphoSitePlus, UniProt, PRO ontology, and text mining. Returns UniProt IDs, PTM site counts, enzyme/substrate roles, and isoform counts.

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 104ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "max_results": {
      "default": 25,
      "description": "Maximum results to return (default: 25)",
      "maximum": 100,
      "minimum": 1,
      "type": "integer"
    },
    "operation": {
      "description": "Operation type",
      "enum": [
        "search"
      ],
      "type": "string"
    },
    "ptm_type": {
      "description": "Filter by PTM type: Phosphorylation, Acetylation, Ubiquitination, Methylation, Sumoylation, N-Glycosylation, O-Glycosylation, S-Nitrosylation, etc. Case-sensitive. Omit to return all types.",
      "type": [
        "string",
        "null"
      ]
    },
    "query": {
      "description": "Gene name, protein name, or keyword to search (alias for search_term)",
      "type": "string"
    },
    "role": {
      "default": "Substrate",
      "description": "Filter by protein role. Substrate = proteins that are modified; Enzyme = proteins that modify others. Default: Substrate",
      "enum": [
        "Substrate",
        "Enzyme",
        "Substrate,Enzyme"
      ],
      "type": "string"
    },
    "search_term": {
      "description": "Search query: gene name (TP53, EGFR, AKT1), protein name (p53, insulin receptor), or keyword (kinase, ubiquitin)",
      "type": "string"
    },
    "term_type": {
      "default": "All",
      "description": "Type of search term. Default: All (searches across all fields)",
      "enum": [
        "All",
        "UniProtID",
        "UniProtAC",
        "GeneName",
        "ProteinName"
      ],
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default IPTMnet Search call

public-safeinput

{
  "max_results": 1,
  "query": "BRCA1"
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_iPTMnet_search
Tool name: iPTMnet_search
Added: 2026-04-30 22:47Z
Tags: tooluniverse

IPTMnet Search

Livelast probed 2026-04-30 23:07Z· 104msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "max_results": { "default": 25, "description": "Maximum results to return (default: 25)", "maximum": 100, "minimum": 1, "type": "integer" }, "operation": { "description": "Operation type", "enum": [ "search" ], "type": "string" }, "ptm_type": { "description": "Filter by PTM type: Phosphorylation, Acetylation, Ubiquitination, Methylation, Sumoylation, N-Glycosylation, O-Glycosylation, S-Nitrosylation, etc. Case-sensitive. Omit to return all types.", "type": [ "string", "null" ] }, "query": { "description": "Gene name, protein name, or keyword to search (alias for search_term)", "type": "string" }, "role": { "default": "Substrate", "description": "Filter by protein role. Substrate = proteins that are modified; Enzyme = proteins that modify others. Default: Substrate", "enum": [ "Substrate", "Enzyme", "Substrate,Enzyme" ], "type": "string" }, "search_term": { "description": "Search query: gene name (TP53, EGFR, AKT1), protein name (p53, insulin receptor), or keyword (kinase, ubiquitin)", "type": "string" }, "term_type": { "default": "All", "description": "Type of search term. Default: All (searches across all fields)", "enum": [ "All", "UniProtID", "UniProtAC", "GeneName", "ProteinName" ], "type": "string" } }, "required": [], "type": "object" }