Cortexa research tool·structure·intact

Intact Get Interaction Network

Get interaction network centered on a specific interactor. Uses EBI Search API (IntAct domain) for reliable access. Accepts IntAct identifiers (e.g., 'EBI-1004115'), UniProt IDs (e.g., 'P04637'), or gene names (e.g., 'BRCA1'). Returns interactions with interaction IDs in the 'interaction_ids' field. These IDs can be used with intact_get_interaction_details for detailed information.

Livelast probed 2026-04-30 23:07Z· 677msCortexa

Status

The most recent probe succeeded. Safe to call from the agent today.

Last probed: 1d ago
Last success: 1d ago
Last latency: 677ms

Schema

JSON Schema the agent (or your API call) must match.

{
  "properties": {
    "depth": {
      "default": 1,
      "description": "Network depth: 1 for direct interactions only, 2 for 2-hop network, etc. (default: 1)",
      "maximum": 3,
      "minimum": 1,
      "type": "integer"
    },
    "format": {
      "default": "json",
      "enum": [
        "json",
        "xml"
      ],
      "type": "string"
    },
    "gene_name": {
      "description": "Alias for identifier: gene name.",
      "type": "string"
    },
    "gene_symbol": {
      "description": "Alias for identifier: gene symbol (e.g., 'BRCA1').",
      "type": "string"
    },
    "identifier": {
      "description": "IntAct identifier, UniProt ID, or gene name. Aliases: uniprot_id, protein_id, gene_symbol, gene_name.",
      "type": "string"
    },
    "limit": {
      "default": 50,
      "description": "Maximum number of interactions to return (default: 50, max: 200). Alias: size.",
      "type": "integer"
    },
    "protein": {
      "description": "Alias for identifier. Gene symbol or protein name (e.g., 'TP53', 'BRCA1').",
      "type": "string"
    },
    "protein_id": {
      "description": "Alias for identifier: protein identifier.",
      "type": "string"
    },
    "protein_name": {
      "description": "Alias for gene_symbol/identifier. Common protein name (e.g., MDM2, TP53).",
      "type": "string"
    },
    "size": {
      "default": 50,
      "description": "Alias for limit. Maximum number of interactions to return (default: 50).",
      "type": "integer"
    },
    "uniprot_id": {
      "description": "Alias for identifier: UniProt accession (e.g., 'P04637').",
      "type": "string"
    }
  },
  "required": [],
  "type": "object"
}

Examples (1)

Default Intact Get Interaction Network call

public-safeinput

{
  "depth": 1,
  "gene_name": "BRCA1",
  "gene_symbol": "BRCA1",
  "limit": 3,
  "size": 1
}

Expected response keys: success

Anonymous-safe example. Rate-limited; no sign-in required.

Identifiers

Catalog ID: tu_intact_get_interaction_network
Tool name: intact_get_interaction_network
Added: 2026-04-30 22:47Z
Tags: tooluniverse

Intact Get Interaction Network

Livelast probed 2026-04-30 23:07Z· 677msCortexa

Schema

JSON Schema the agent (or your API call) must match.

{ "properties": { "depth": { "default": 1, "description": "Network depth: 1 for direct interactions only, 2 for 2-hop network, etc. (default: 1)", "maximum": 3, "minimum": 1, "type": "integer" }, "format": { "default": "json", "enum": [ "json", "xml" ], "type": "string" }, "gene_name": { "description": "Alias for identifier: gene name.", "type": "string" }, "gene_symbol": { "description": "Alias for identifier: gene symbol (e.g., 'BRCA1').", "type": "string" }, "identifier": { "description": "IntAct identifier, UniProt ID, or gene name. Aliases: uniprot_id, protein_id, gene_symbol, gene_name.", "type": "string" }, "limit": { "default": 50, "description": "Maximum number of interactions to return (default: 50, max: 200). Alias: size.", "type": "integer" }, "protein": { "description": "Alias for identifier. Gene symbol or protein name (e.g., 'TP53', 'BRCA1').", "type": "string" }, "protein_id": { "description": "Alias for identifier: protein identifier.", "type": "string" }, "protein_name": { "description": "Alias for gene_symbol/identifier. Common protein name (e.g., MDM2, TP53).", "type": "string" }, "size": { "default": 50, "description": "Alias for limit. Maximum number of interactions to return (default: 50).", "type": "integer" }, "uniprot_id": { "description": "Alias for identifier: UniProt accession (e.g., 'P04637').", "type": "string" } }, "required": [], "type": "object" }