ScienceBenchmarksDocsCatalogPricing
Sign inStart research
Cortexa/public research

Research people chose to publish

Each page is a real run: the question as asked, the answer with every claim cited, the sources, and the code behind every number. Authors list a run here on purpose — a shared link on its own stays unlisted.

17 published runs

  • 30 Sept 2026

    Structure: render the best available experimental structure of the ADAM17 catalytic domain (and the AlphaFold model of…

    Direct answer The best experimental look at the ADAM17 catalytic domain is PDB 2I47 — 1.9 Å X-ray, zinc plus a peptidomimetic hydroxamate inhibitor, and the best-ordered of the ADAM17 catalytic-domain entries I verified…

    91 tool runsRead
Cortexa.

The agent for research teams. 1.9K+ research tools across scientific and professional fields, with sources attached to the claims they support.

Product

  • Cortexa for science
  • Research benchmark
  • Documentation
  • Integrations
  • Tool catalog
  • Security & privacy
  • Pricing

Get started

  • Start research
  • Sign in
  • Developer API
  • MCP server

Support

  • Help center
  • Contact us
  • Terms of Service
  • Privacy Policy

© 2026 Cortexa. All rights reserved.

TermsPrivacy·For research context only · Not medical, legal, or financial advice.
28 Sept 2026

We are a contract protein-production company (cell-free synthesis, E.

ADAM17/TACE (P78536) feasibility workup Recommendation up front: produce the prodomain + catalytic zymogen (residues 18–474) as a secreted CHO transient build (primary), with E.

26 tool runsRead
  • 21 Sept 2026

    Do a real analysis of InduPro's cell-surface proximity atlas, the open dataset behind their Nature paper this month…

    Here's what the analysis found. Across InduPro's proximity atlas, the neighbour that recurs in the most tumor cell lines next to a receptor tyrosine kinase bait is PVR/CD155 near MET (19 of 28 lines), followed by CD44…

    21 tool runsRead
  • 20 Sept 2026

    Test one claim about Lacuna, the open-source cryptic-pocket tool: that it finds the KRAS switch-II pocket (SII-P) as a…

    The paired test contradicts the tool's claim on this one structure pair: Lacuna scored the KRAS switch-II pocket (SII-P) as more cryptic in the sotorasib-open holo structure (6OIM) than in the ligand-free apo structure…

    11 tool runsRead
  • 18 Sept 2026

    These are three sheets from the construction set of 255 Shipley Street, San Francisco (a four-storey-over-basement…

    Massing card accepted — it builds in your browser after this turn, so I'll tell you what to check below.

    28 tool runsRead
  • 18 Sept 2026

    The two attached images are a 1920 kit-house floor plan (Harris Home No.

    The 3D model is built from the dimensions on the plan and is now compiling in your browser (it finishes after this turn — the card's breadcrumb will confirm the measured size).

    1 tool runRead
  • 16 Sept 2026

    Build a pipe flange: 120 mm outer diameter, 50 mm bore, 10 mm thick, six 9 mm bolt holes on a 95 mm bolt circle, and a…

    Yes — it built, and it matches the drawing. The strongest evidence is the volume: the measured 95.77 cm³ agrees with the value the dimensions alone predict, which only happens if all six holes are present at the right…

    2 tool runsRead
  • 16 Sept 2026

    Design a robot arm link in 6061 aluminium as one solid part, exactly to these dimensions, and give me a STEP file for…

    Yes — I built a simplified 3D structural representation of the machine in your photo.

    6 tool runsRead
  • 16 Sept 2026

    Design a small enclosure lid for me: 90 mm long, 60 mm wide, 2 mm thick, corners rounded 4 mm, with four 2.8 mm screw…

    GLP-1 receptor agonists — semaglutide in particular — reduce some alcohol-consumption outcomes in humans, but the randomized evidence is still early and concentrated in patients with comorbid obesity.

    11 tool runsRead
  • 12 Sept 2026

    What does the LOCUS preprint (arXiv 2609.11739) show about preference tuning making language models verbose, and how…

    LOCUS (arXiv:2609.11739, Task-Aware Low-Rank Post-Training for Token-Efficient Language Generation, Dongfang Zhao, submitted 10 Sep 2026) argues that standard preference alignment often inflates response verbosity…

    8 tool runsRead
  • 12 Sept 2026

    How does Gen-COMPAS (Nature 2026) combine a diffusion model with committor estimates to find protein conformational…

    Gen-COMPAS (Tang, Pandey, Chen, Megías, Dehez & Chipot, Nature 2026) is an iterative loop that pairs a denoising diffusion generative model with a learned committor function to find the transition states of rare…

    7 tool runsRead
  • 12 Sept 2026

    What did the Dyna-1 paper (Nature 2026, Scripps Research) show about predicting millisecond protein dynamics from the…

    Dyna-1 turns a longstanding nuisance in protein NMR — residues that simply never show up in the spectrum — into a usable, learnable signal for where a protein is moving on the microsecond-to-millisecond timescale, and a…

    7 tool runsRead
  • 25 Aug 2026· abstract

    Pull GSE52778 from GEO and tell me which genes respond to dexamethasone in airway smooth muscle cells, and why.

    GSE52778 profiled primary human airway smooth-muscle (ASM) cells from four donor lines (16 RNA-seq samples) under untreated versus 1 µM dexamethasone for 18 hours. Analysis of the gene-level Dex-versus-untreated…

    1 source cited9 tool runsRead
  • 18 Aug 2026· abstract

    Do GLP-1 receptor agonists improve kidney outcomes in chronic kidney disease?

    In type 2 diabetes and CKD, once-weekly semaglutide (FLOW) is the single trial prospectively powered on a kidney composite and shows a significant reduction extending beyond albuminuria…

    10 sources cited10 tool runsRead
  • 3 Aug 2026

    I am writing a book around the premise that GLP-1 pervasiveness is a therapeutic response to a dyregulated culture,…

    . The modern gold standard for quantifying social connectedness against economic outcomes.

    14 tool runsRead
  • 7 Jul 2026

    For linked in, instagram, and X social media posts for business marketing purposes in the tech/medicine sector, what…

    Here's the post ready to ship, then the media and mechanics that actually move engagement. Final draft > Scut work is the tax you pay for doing research. > > The literature triage. The reformatting.

    10 tool runsRead
  • 13 May 2026· abstract

    Can you evaluate the "future directions" section of the most high-impact research papers published in pain medicine…

    A systematic gap analysis of 28 high-impact pain medicine papers (2014–2025) identified five major "future directions" with the greatest shortfall between recommendation frequency and follow-through research.…

    8 sources cited79 tool runsRead

    • Publish your own

    Run a question in Cortexa, press Share, and tick List in the public research gallery. Untick it at any time and the run leaves this page and the sitemap on the next request.

    Start a run